Synthesis, antidiabetic activity and molecular docking study of rhodanine-substitued spirooxindole pyrrolidine derivatives as novel α-amylase inhibitors
Collected date : from 2017 to 2020
In a sustained search for novel α-amylase inhibitors for the treatment of type 2 diabetes mellitus (T2DM), we report herein the synthesis of a series of nineteen novel rhodanine-fused spiro[pyrrolidine-2,3′-oxindoles]. They were obtained by one-pot three component [3 + 2] cycloaddition of stabilized ...
Clay mineralogical and geochemical expressions of the "Late Campanian Event" in the Aquitaine and Paris basins (France): Palaeoenvironmental implications
Collected date : from 15 Aug 2013 to 15 May 2014
Campanian sediments from two French sedimentary basins were studied, using clay mineralogy and stable isotope (δ13C and δ18O) geochemistry, in order to investigate the Late Campanian Event. The clay fraction of the Campanian sediments from the Tercis-les-Bains section (Aquitaine Basin) and from the ...