Data on genes expression in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative Human opportunistic pathogen, responsible for nosocomial infections with high mortality for immunocompromised patients. The pathogenesis is based on the production of many structural or secreted virulence factors. P. aeruginosa is also able to produce ...
New spiropyrrolothiazole derivatives bearing an oxazolone moiety as potential antidiabetic agent: Design, synthesis, crystal structure, Hirshfeld surface analysis, ADME and molecular docking studies
In a sustained search for novel and effective antihyperglycemics, a new series of fifteen isomeric oxazolone-fused dispiropyrrolothiazoles resulting from one-pot three component reaction between L-4-thiazolidine carboxylic acid, arylidene-oxazolones and isatin (or acenaphthenequinone) has been ...
Antimicrobial Activity and DFT Studies of a Novel Set of Spiropyrrolidines Tethered with Thiochroman-4-one/Chroman-4-one Scaffolds
A novel series of 14 spiropyrrolidines bearing thiochroman-4-one/chroman-4-one, and oxindole/acenaphthylene-1,2-dione moieties were synthesized and characterized by spectroscopic techniques, as well as by three X-ray diffraction studies, corroborating the stereochemistry. Quantum chemical ...
Synthesis, antidiabetic activity and molecular docking study of rhodanine-substitued spirooxindole pyrrolidine derivatives as novel α-amylase inhibitors
In a sustained search for novel α-amylase inhibitors for the treatment of type 2 diabetes mellitus (T2DM), we report herein the synthesis of a series of nineteen novel rhodanine-fused spiro[pyrrolidine-2,3′-oxindoles]. They were obtained by one-pot three component [3 + 2] cycloaddition of stabilized ...
Pollen analysis - Les Rousses (F-39), Les Rousses lake
Natural site: peat bog near the lake's outlet. 16 palynological samples. The selection was made in several drillings. Two pollen tests performed in 2021 towards the lake outlet.
Diversity-oriented Synthesis of Spiropyrrolo[1, 2-a]isoquinoline Derivatives via Diastereoselective and Regiodivergent Three-component 1,3-Dipolar Cycloaddition Reactions: In vitro and in vivo Evaluation of the Antidiabetic Activity of Rhodanine Analogues
An efficient diastereoselective route is developed to get access to novel spiropyrrolo[1,2-a]isoquinoline-oxindole skeletons by a one-potthree-component [3 + 2] cycloaddition reaction of (Z)-5-arylidene-1,3-thiazolidine-2,4-diones, isatin derivatives, and 1,2,3,4-tetrahydroisoquinoline (THIQ). ...
Control of Structures and Emission Properties of (CuI)n 2-Methyldithiane Coordination Polymers
A structurally unique and strongly luminescent nonporous 3D coordination polymer (CP) [Cu8I8(methyldithiane)4]n, CP3, has been prepared in a quasi-anticipated manner from 2-methyl-1,3-dithiane, L1, and CuI. This CP incorporates an unprecedented Cu8I8 cluster built upon two side-fused open cubanes. ...
A Fused Poly(truncated rhombic dodecahedron)-Containing 3D Coordination Polymer: A Multifunctional Material with Exceptional Properties
The design of new and inexpensive metal-containing functional materials is of great interest. Herein is reported a unique thermochromic near-IR emitting coordination polymer, 3D-[Cu8I8(L1)2]n, CP2, which is formed when ArS(CH2)4SAr (L1, Ar = 4-C6H4OMe) reacts with 2 equiv of CuI in EtCN. In MeCN, ...
Crystal structure of di-[mu]-iodido-bis[bis(acetonitrile-[kappa]N)copper(I)]
The title compound, [Cu2I2(CH3CN)4], exhibits a centrosymmetric Cu2I2 core [Cu...Cu distance = 2.7482 (11) Å], the CuI atoms of which are further coordinated by four molecules of acetonitrile. The CuI atom has an overall distorted tetrahedral coordination environment evidenced by L-Cu-L angles (L ...
Crystal structure of di-[mu]-iodido-bis[(dimethyl sulfoxide-[kappa]O)(triphenylphosphane-[kappa]P)copper(I)]
The centrosymmetric dinuclear title compound, [Cu2I2(C2H6OS)2(C18H15P)2], represents the first example of a CuI complex ligated by an O-bound dimethyl sulfoxide ligand. In the crystal, the two tetrahedrally coordinated CuI atoms are bridged by two [mu]2-iodido ligands in an almost symmetrical ...
Crystal structure of the two-dimensional coordination polymer poly[di-μ-bromido-bis(μ-tetrahydrothiophene)dicopper(I)]
The polymeric title compound, [Cu2Br2(C4H8S)2]n, CP1, represents an example of a two-dimensional coordination polymer resulting from reaction of CuBr with tetrahydrothiophene (THT) in MeCN solution. The two-dimensional layers consist of two different types of rhomboid-shaped dinuclear ...
Pollen analysis - Le Miroir (F-71), La Tuilerie (La Peupleraie), A39-T1 and T2
Natural site over the alignment of the A39 motorway; drilling. Two series: T1 (18 poor samples) and T2 (88 palynological samples + 2 radiocarbon datings). Samples often difficult to read. Publication CRAS, 1996.
Pollen analysis - Auneau (F-28), L'Hermitage (detour road 18/116/19)
Natural site: drilling with motorised "russian" core. 120 palynological samples. + 6 radiocarbon datings. 2015 publication: only the "gallo-roman" part.
Pollen analysis - Villers-le-Lac (F-25), La Roche aux pêcheurs
Archaeological site: rock shelter. 10 palynological samples. Only one acceptable result. Archaeological excavation: Ch. Cupillard, SRA de Franche-Comté.
Pollen analysis - Fontenu (F-39), îlot David-1987, FG 30, 86 S-C, 86 G23
Archaeological site. Lake dwelling. 9 palynological samples (related to M. Magny PhD thesis, 1991).
Pollen analysis - Fontenu (F-39), Lac de Chalain, îlot David, A 33/34
Archaeological site. Lake dwelling. 11 palynological samples.
Pollen analysis - Héricourt (F-70), La Lizaine (chemin de l'usine)
Archaeological excavation of rural settlement. 7 palynological samples. Approximate geographical coordinates.
Pollen analysis - Grozon (F-39), L'étang (Marais)
Natural site: wooded swamp. 144 palynological samples with 2 radiocarbon datings. Sometimes quite poor. Further analyses were done in the village of Grozon around the salt springs by E. Gauthier (PhD, 2001).
Pollen analysis - Clairvaux-les-lacs (F-39), Station II
Archaeological site. Lake dwelling. 14 palynological samples + radiocarbon and dendrochronological datings.
Pollen analysis - Bonlieu (F-39), Le Lautrey (point 205)
Peat bog; 51 palynological samples. Other analyses on this site by Carole Bégeot and Pascale Ruffaldi (2006)
Pollen analysis - Andelot-en-Montagne (F-39), Marais (KTH)
Peat bog. 9 palynological samples. KTH testing (see : Sjörgen, P. 2007. Mires and Peat, International Mire Conservation Group and International Peat Society ; Gobet, 2014)
Pollen analysis - Auneau (F-28), 1996 : Le Parc du Château, forage A10
Natural site: drilling. 71 palynological samples + 4 radiocarbon datings (one is wrong, too recent). Malacological studies by Nicole Limondin (1997).
Pollen analysis - Boécourt (Suisse, Jura), Les Pécats (Les Montoyes)
Natural site: section. 44 palynological samples. Sterile or unavailable samples.
Pollen analysis - Corsier (Suisse, Genève), Marina
Lacustrin archaeological site: sub-lake drilling. 25 palynological samples in the core C1
Pollen analysis - Boncourt (Suisse, Jura), Le Neu Bois
Natural site: geological section. 13 palynological samples. Almost all sterile.
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