Data on genes expression in Pseudomonas aeruginosa
Collected date : from Dec 2017 to Dec 2020
Creators :
Mélanie Grosjean
Pseudomonas aeruginosa is a Gram-negative Human opportunistic pathogen, responsible for nosocomial infections with high mortality for immunocompromised patients. The pathogenesis is based on the production of many structural or secreted virulence factors. P. aeruginosa is also able to produce ...
3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species
Disciplines :
chemistry, organic
biochemistry & molecular biology
Collected date : from Jan 2017 to Oct 2018
Based on N-acyliminium species, efficient approaches to spirocyclic systems connected by two different carbon centers to the isoindole ring have been developed. The imide reduction and the tandem oxidative cleavage of olefin/formyl-amide equilibration were at first selected as the key steps for ...
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