Mohamed Othman

Structure : Normandie Université - Université Le Havre

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3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species

Based on N-acyliminium species, efficient approaches to spirocyclic systems connected by two different carbon centers to the isoindole ring have been developed. The imide reduction and the tandem oxidative cleavage of olefin/formyl-amide equilibration were at first selected as the key steps for ...

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